MESCTI & ADB

About MACRO PROJECT

This macro project was initiated by the Technical Committee Advice for COVID-19 (Grupo Técnico para Apoio ao Plano Nacional de Contigência e Emergência Contra a COVID-19 (GTC) from the Ministry of Higher Education, Science, Technology and Innovation and sponsored by the African Development Bank. It is made of four subprojects (Clinical Epidemiology, Protective factors, Kinetics of viral loads and genomic sequencing)  and expects to contribute to a better understanding of the epidemiological, clinical and laboratory profile against SARSCOV-2 infection and produce evidence to improve prevention, control and treatment of COVID-19 in Angola.

Viral load kinetics of SARS-CoV-2 infection in Angolan patients

Image by Julia Koblitz

The proposed study intends to obtain results that reflect an evaluation of the results with a broad reflex and of fundamental character to determine: The stage of the infection (mild, moderate and severe) based on the corresponding clinical radiological findings and viral concentration; The optimal time for antiviral treatment intervention to prevent disease progression; The best orientation in the asymptomatic patient; What type of sample reveals a higher concentration of virus and thus better guide the health professional; Correlation of viral concentration and onset of symptoms.

Genomic characterization of SARS-Cov-19 in individuals diagnosed with COVID-19 in Angola.

The world is currently facing the pandemic of the novel coronavirus disease (COVID-19), a viral disease that can progress to severe acute respiratory disease (SARS). 

 

The sequencing of the viral genome makes it possible to know its structure and compare it with those of published results from other regions, serving as a basis for epidemiological studies and for defining and monitoring the type of mutation, if any, that may affect clinical and diagnostic interventions. and the effectiveness of the vaccines to be applied. 

This study aims at characterizing the SARS-COV-2 viral genome of patients diagnosed with COVID-19 in Angola.

Image by National Cancer Institute